Capabilities

The Reputable
Research Cycle.

From real-world evidence to randomized controlled trials. Supplements, devices, and behavioral protocols. One team, from recruitment to clinical study report.

Design your study

Research signals represented through wearable measurement

By the numbers

Everything we have actually run.

How quickly we recruit, how consistently people participate, and the community behind the work.

Recruitment

12.6 days

Average full enrollment across our most recent completed clinical studies

Compliance

~87%

Average compliance across our most recent completed clinical studies

Returning participants

82%

Of participants are returning, already vetted and study-ready

Studies run

70+

Sponsored studies, excluding public learning studies

The stack

What we run, and how we prove it.

Design and category are separate decisions. The category determines what we measure. The design determines how the claim holds up under scrutiny.

Design

Real-World EvidenceRandomized Controlled Trial

The design follows the claim, from real-world evidence through randomized trials and the options between them. Longitudinal designs with rolling enrollment, and pre-trial or post-market surveillance, are supported where the question calls for them.

Supplements Devices Behavior

The category changes what we measure, while every study follows the same protocol discipline.

Signals

Layer the right measures

Continuous wearable monitoring · Validated surveys · Blood labs · Methylation testing and epigenetic age · Cognitive assessment · Smart scales · Urinalysis, baseline and end-of-study

Explore the study spectrum See study categories

Choosing a design

The Study Spectrum.

Real-world evidence and randomized trials are the two ends. Where your claim lands sets the timeline, the budget, and what the result can support. Studies are typically completed within 2 to 6 months, depending on recruitment complexity and intervention duration.

RWE Pilot

Early validation and initial substantiation

Wearable and survey signals that test early marketing claims and product-market fit.

n = ~35 participants

RWE Phase 1

Health claims development and substantiation

A powered, confirmatory design that builds on early validation, gathering scaled evidence from participants' daily lives.

n = ~100 to 500+ participants

RCT Pilot

Initial substantiation

A controlled design that tests causality before a full trial.

n = ~70 participants

RCT Phase 1

Regulatory &
commercial evidence

A randomized trial powered for the primary endpoint.

n = ~160 to 500+ participants

Starting points, not fixed tiers. Every package scales to your product, your claims, and your budget. Marketing claims are not tied to a single phase. When your results support them, claims can start at pilot, and later phases add power and confirmation.

Participant numbers shown are starting ranges. We recommend a power analysis for every study to determine the final sample size.

What we run

Three kinds of study, one operating model.

Different interventions. The same disciplined path to usable evidence.

Latina participant preparing an unbranded supplement as part of an at-home study routine

Ingredients and supplements

Objective and subjective measures, read together.

Continuous wearable data, blood labs, and validated surveys let objective and subjective measures be read together.

Published on PubMedPeer-reviewed supplement studyView the article

Black male participant wearing a smartwatch while reviewing a study check-in on a phone outdoors

Devices

Run at home. Log continuously.

Participants use their own devices at home, with adherence logged continuously instead of reconstructed later.

~87%Participant completion in device studiesDesigning around hardware

Behavioral interventions

Measure the behavior itself.

Apps and guided protocols require adherence and outcomes to be measured around the behavior itself.

Why this matters

Our studies average ~87% compliance across our most recent completed clinical studies, including protocols with blood draws, methylation testing, and cognitive assessments layered on.
That is protocol design, participant experience, and an engagement system built across 70+ studies. If your brand needs evidence that people actually finish generating, that is the problem we have spent our time solving.