What Nestlé Sold for $1 Billion, and What It Refused to Sell
Nestlé sold $1.2 billion in supplement revenue for $1 billion and kept its science-led brands. The other side of the pattern we wrote about in August.
Read articleFor Brands10 articles
The Biggest Supplement Wins of 2026 All Have One Thing in Common
Thorne, Grüns, and IM8 posted three of the year's largest outcomes in four months. Different companies, different categories, different deal structures, and one pattern: the brands...
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Should I Run a Pilot First?
A pilot tests whether you can run the study, not whether the product works. Learn when pilots help, when they create risk, and what FTC guidance...
Read articleEvidence-Based Testimonials: Why They Matter in Health and Wellness
Evidence-based testimonials are transforming wellness marketing. By pairing personal stories with wearable data and validated outcomes, they offer consumers proof, not just promises, building trust, ensuring compliance,...
Read articleHealth and Wellness Research Trends To Look Out for in 2025
Discover the top health and wellness research trends set to revolutionize 2025. Explore how advancements in AI and genetic testing are driving personalized nutrition, offering tailored...
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Why Are Clinical Trials Important for Your Wellness Product?
Discover why conducting clinical trials is crucial for your wellness product’s success. This article explains how clinical trials confirm your product’s safety and effectiveness, providing scientific...
Read articleHow Running a Study Can Supercharge Your Marketing Strategy
In today's crowded health and wellness market, where every brand claims to offer the next groundbreaking product, distinguishing yourself can feel like an uphill battle. The...
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Behind the Claims: How Real-World Data Shapes Health Product Credibility
Learn how to communicate supplement research accurately, assess whether evidence applies to your product, and explain study limitations before making marketing claims.
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How Health Brands Can Win Consumer Trust
In the competitive wellness industry, backing up health claims with solid scientific evidence is key to credibility and regulatory compliance. But how do you get started?
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3 Best Practices for Real-World Health Studies in 2025
Real-world health studies are essential for understanding how medical treatments work outside clinical trials, offering insights into their effectiveness, safety, and cost-efficiency. This article explores key...
Read articleEducation32 articles
How to Choose a Research Partner for a Sleep Supplement Study
Before comparing quotes, ask every research partner to explain how they would answer the same sleep question. Two proposals can both include a wearable and a...
Read articleClinical Trial Software for Brands and Ingredient Manufacturers
About the author Mackenzie De Jesus, DHSc, MS, Head of Clinical Research. Mackenzie De Jesus, DHSc, MS, leads clinical research at Reputable Health, where she designs...
Read articleClinical Trial Data Management: From Protocol to Database Lock
About the author Mackenzie De Jesus, DHSc, MS, Head of Clinical Research. Mackenzie De Jesus leads clinical research at Reputable Health, where she designs and runs...
Read articleClinical Trial Management System: Buy One or Use Your CRO’s?
About the author Mackenzie De Jesus, DHSc, MS, Head of Clinical Research. Mackenzie De Jesus leads clinical research at Reputable Health, where she designs and runs...
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Contract Research Organizations: Which Kind Fits Your Claim
Five kinds of contract research organization, for health and wellness brands and ingredient manufacturers, and how to match each CRO type to your claim.
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Clinical Trial Outsourcing: What to Hand Off and What to Keep
How clinical trial outsourcing works for health and wellness brands and ingredient manufacturers: four models, what to keep in-house, and oversight.
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Decentralized clinical trials and real-world evidence
Reputable Health put together this practical guide for health and wellness brands and ingredient manufacturers: what decentralized clinical trials and real-world evidence are, when they fit,...
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Real-World Evidence for Supplement Brands and Ingredient Manufacturers
Learn how supplement brands and ingredient manufacturers can plan real-world research, evaluate data quality, and understand what findings can support.
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Structure/Function Claims: What Evidence Do Supplement Brands Need?
Learn what evidence supplement structure/function claims need, how they differ from disease claims, and what to review before using them.
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Clinical Studies for Ingredient Manufacturers: A Buyer’s Guide
Plan clinical studies for ingredient manufacturers: compare designs, outcomes, CRO proposals, costs and deliverables, and understand what results can support.
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Reputable vs a Traditional CRO: Which Fits Your Supplement Study?
Compare a traditional site-based CRO with Reputable's decentralized, wearable-based studies for supplement brands: when each fits and the tradeoffs.
Read articleHow to Read Clinical Trial Data
Learn how to read clinical trial data and its statistical analysis: study design, endpoints, p-values, confidence intervals, effect sizes, and red flags.
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What Is Good Clinical Practice (GCP) in Clinical Trials
Good Clinical Practice (GCP) is the international ethical and scientific standard for designing, conducting, recording, and reporting human trials.
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Do Wellness Products Need FDA Approval? A Guide for Brands
Learn which wellness products need FDA approval, how registration differs from approval, and what to check in manufacturing records, laboratory tests and clinical evidence.
Read articleIs Melatonin Regulated by the FDA?
Melatonin is regulated as a dietary supplement under DSHEA of 1994, not as an FDA-approved drug. Content can vary; look for third-party tested products.
Read articleCRF Meaning: What Is a Case Report Form (CRF)?
In clinical trials, CRF means case report form: the paper or electronic record of each participant's study data. See what a CRF holds and how eCRFs...
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What Is a Phase 2 Clinical Trial?
Phase 2 clinical trials test effectiveness and safety in a few dozen to a few hundred participants to see if a treatment warrants Phase 3 study.
Read articleWhat Is a CRO in Clinical Trials
CRO stands for contract research organization, the company a sponsor hires to run a clinical study. See what CROs do, the main types, and how to...
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What Is CTMS in Clinical Trials
A CTMS (Clinical Trial Management System) centralizes planning, tracking, monitoring, finance, and reporting to keep complex trials on track.
Read articleHow to Report SAE in Clinical Trials
SAEs include death, life-threatening risk, hospitalization, disability, or congenital abnormalities. Report promptly, often within 24 hours of awareness.
Read articleDo Private Companies Need IRB Approval?
Private companies generally need IRB approval for human subjects research, including clinical trials, surveys, and identifiable medical data analysis.
Read articleAre Sleep Supplements FDA Approved?
Sleep supplements fall under DSHEA of 1994, not pre-approval like drugs. Makers follow GMPs and may use structure/function claims backed by evidence.
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When Is IRB Approval Required?
IRB approval is required for research with human subjects that is a systematic investigation intended to produce generalizable knowledge.
Read articleHow Long Does It Take to Get IRB Approval for Health Wearable Tech?
Planning a health study using wearable technology? Find out how long it takes to get IRB approval and what influences the timeline. This comprehensive guide explains...
Read articleWhat Is IRT In Clinical Trials with Wearable Tech?
Discover how Interactive Response Technology (IRT) is revolutionizing clinical trials by automating essential processes like patient randomization, drug supply management, and real-time data analytics. Learn how...
Read articleAre Clinical Trials Safe? (And Why Wearable Trials are Safest)
Wondering if clinical trials are safe? This comprehensive guide delves into the multiple layers of safety protocols in place, including IRBs, informed consent, DSMBs, and FDA oversight, to...
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Understanding “Clinically Proven” vs. “Clinically Tested” in Wellness Marketing
In the highly competitive wellness industry, terms like “clinically proven” and “clinically tested” are frequently used to enhance product credibility. However, these phrases are not interchangeable....
Read articleWhy Do Clinical Trials Fail?
Discover why 90% of clinical trials fail and learn how to increase your success rate in the wellness industry. This article delves into common pitfalls like...
Read articleWhat is a Phase 1 Clinical Trial in Behavioral Commercial Health?
Discover how Phase 1 clinical trials in behavioral commercial health are pioneering non-pharmaceutical interventions to enhance mental wellness and overall health. This article explores the objectives...
Read articleWhat is EDC in Clinical Trials?
Discover how Electronic Data Capture (EDC) systems are revolutionizing clinical trials by streamlining data collection, improving accuracy, and ensuring data integrity. This comprehensive guide explores the...
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Compliance Made Easy: Your Guide to FTC and FDA Rules
Navigating FTC and FDA compliance can feel like a maze, but it’s key to the success and credibility of your wellness products. This guide will break...
Read articleData Science7 articles
How to Fact-Check Supplement Claims With AI
Use AI to find claims and citations, then verify each source on PubMed or ClinicalTrials.gov. Treat AI as an assistant, not the final word on evidence.
Read articleAdvancing Neurocognitive Research through Real-World Evidence
The future of cognitive health research is here. In this white paper, Reputable Health outlines a cutting-edge model combining brainwave data, wearable biometrics, and molecular analysis...
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Real-World Data vs Clinical Trials
Understand how real-world data, observational studies and clinical trials differ, and how to match study design to your research question and proposed claims.
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PubMed vs Google Scholar: Which to Use and When
Trying to decide between Google Scholar and PubMed for your clinical research? This comprehensive guide compares both platforms, highlighting Google Scholar’s broad, interdisciplinary coverage ideal for...
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Mastering PubMed and Google Scholar: Tips to Overcome Research Intimidation
When it comes to diving into clinical research, PubMed and Google Scholar are like treasure troves of scientific information. But let's be honest, they can feel a...
Read articleHow AI is Shaking Up Health Research
Artificial intelligence (AI) is revolutionizing health research and compliance, offering groundbreaking ways to boost study accuracy and streamline regulations. Reputable’s compliance engine is leading the charge,...
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The Power of Data: Transforming Clinical Trials for Better Outcomes
In the wellness industry, Reputable Health uses data-driven validation to ensure product efficacy and credibility. By leveraging scientific rigor and independent validation, we enhance trustworthiness and...
Read articleWearable Tech6 articles
Centralized vs Decentralized Clinical Trials
Compare centralized and decentralized clinical trials, including study visits, wearable data, participant burden, oversight, benefits, and tradeoffs.
Read articleA Guide to Wearables in Decentralized Clinical Trials
Wearables support decentralized clinical trials with continuous remote data on heart rate, sleep, activity, and recovery scores, giving researchers real-time data for studies in everyday settings.
Read articleWearables in Clinical Trials: Pros and Cons
Wearables in clinical trials improve precision and cut clinic visits, but add privacy, data security, and multi-source data management challenges.
Read articleWhat are Decentralized Clinical Trials? (And How Wearables Facilitate Them)
Discover how Decentralized Clinical Trials (DCTs) are revolutionizing clinical research by leveraging wearable technology for remote participation and real-time data collection. This article delves into the...
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From Heartbeats to Sleep Cycles: The Power of Wearable Metrics in Health Studies
Wearable devices like the Oura Ring, Whoop, and Apple Watch have become essential in health research, offering real-time data on various physiological metrics. These devices provide...
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Wearable Tech: The New Frontier in Health Research
Wearable technology, like the Oura Ring and Whoop, has transformed health research by providing real-time data on metrics such as heart rate, sleep, and activity levels....
Read articleWearable Metrics4 articles
How Does WHOOP Calculate Strain?
How WHOOP turns heart rate zones and muscular load into a 0 to 21 Strain score, why the scale is logarithmic, and why your max heart...
Read articleWhy Is My Readiness Score So Low on My Oura?
Why your Oura Readiness Score dropped, what each score range means, what 'Pay attention' on Recovery Index means, and simple ways to raise it again.
Read articleWhat Is Strain in WHOOP?
What your WHOOP Strain score means, the 0-21 zones from Light to All Out, what counts as a good score for your recovery, and how Day...
Read articleWhat Is Readiness Score for Oura?
Oura Readiness Score (0 to 100) shows how prepared your body is for the day based on sleep, activity, resting heart rate, HRV, and body temperature.
Read articleComparisons7 articles
Reputable Health vs Citruslabs vs Radicle Science
Compare Reputable Health, Citruslabs and Radicle Science by study approach, measurements, responsibilities and evidence. Use a shared brief to assess fit.
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5 Best Alternatives to Medeloop in 2025
Compare five Medeloop alternatives for clinical trial management, from consumer health evidence programs to enterprise and academic EDC options.
Read articlePeople Science Alternatives: Comparing Research Providers
Compare People Science alternatives for wellness research by study design, measurements, responsibilities and evidence. Use a shared brief to evaluate proposals.
Read article5 Best PRUVN Alternatives in 2025
Compare five PRUVN alternatives for wellness research, covering wearable data collection, end-to-end trial support, and FDA and FTC compliance focus.
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5 Best Evidation Alternatives to Try in 2025
Looking for a more reliable platform than Evidation for your health and wellness journey? Discover the 5 best Evidation alternatives to try in 2025. This comprehensive...
Read article5 Best Radicle Science Alternatives for Clinical Trials in 2025
Looking for better options than Radicle Science for your clinical trials? Explore the 5 best Radicle Science alternatives for 2025 that offer affordable, efficient, and customizable...
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Citrus Labs Alternatives: Choosing a Research Partner for Your Brand
Comparing Citrus Labs alternatives? Explore research providers and learn what to ask about study design, recruitment, data collection, and support.
Read articleIndustry Trends6 articles
The Need for More Research in Women’s Health
The landscape of health research is continuously evolving, driven by advancements in technology, shifts in regulatory standards, and a growing recognition of the importance of personalized...
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The Evolution of Health Research
In the last decade, the commercial health industry has seen explosive growth, driven by an increasing demand for alternative, personalized solutions to health. Unfortunately, the scientific...
Read articleJoin the Wellness Study That Rewards Your Health
If you're already using an Oura Ring or Whoop, you’re likely someone who prioritizes your health and well-being. But have you ever considered how much more...
Read articlePersonalizing the Research Journey in Health Studies
The landscape of health research is continuously evolving, driven by advancements in technology, shifts in regulatory standards, and a growing recognition of the importance of personalized...
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The Future of Wellness Research: Trends, Innovations, and Breakthroughs
The wellness industry is on the cusp of a revolution, driven by emerging trends, innovative technologies, and a growing demand for data-driven solutions. As consumers become...
Read articleThe Evolution of Health Research: Bridging the Gap Between Innovation and Scientific Evidence
In the last decade, the commercial health industry has seen explosive growth, driven by an increasing demand for alternative, personalized solutions to health. Unfortunately, the scientific...
Read articleTrust & Regulatory1 article
Supplement Claim Substantiation: What Actually Counts as Evidence
Supplement claim substantiation turns on two questions: which kind of claim the product may make, and what evidence must exist before you advertise it. Here is...
Read articleClinical research
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